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Top Gainers & Losers Today

The biggest movers of the regular trading session. These are today's top gainers and losers across the entire US market — every stock ranked by its percentage move, with price and volume — so you can see at a glance what's running and what's getting hit.

For the regular session of Sep 22, 2026, the biggest gainers were RAIN (+60.36%), GRML (+49.47%) and FLNA (+37.93%); the biggest decliners were SDM (-86.41%), NVVE (-44.21%) and CMPX (-32.97%).

Top gainers

#SymbolPriceChg %Volume
1RAIN$1.06+60.36%185.25M
2GRML$14.08+49.47%119.86M
3FLNA$1.02+37.93%1.61B
4VKTX$40.87+35.72%39.62M
5IMCC$4.16+34.85%36.17M
6WTO$9.60+34.45%77.08K
7TPST$1.03+33.11%2.63M
8INDP$4.04+30.74%1.62M
9ZCMD$1.03+29.98%6.56M
10MAZE$28.42+26.93%5.22M
11EPSM$1.58+26.40%
12RAAQ$13.42+24.26%3.5M
13BFLY$9.94+22.05%36.06M
14JTAI$1.79+20.95%122.82M
15DCOY$3.09+20.70%2.56B
16AVAT$2.24+19.79%6.68M
17VICR$268.09+19.73%1.9M
18EAF$11.21+19.71%2.07M
19QMMM$119.40+19.40%721.34K
20AREN$1.12+19.15%121.89M
21IPDN$4.00+19.05%118.83K
22FEAM$2.93+18.15%3.18M
23BALY$12.40+17.42%
24DNA$9.35+17.17%3.6M
25EU$1.23+17.14%27.12M

Top losers

#SymbolPriceChg %Volume
1SDM$1.85-86.41%38.94M
2NVVE$3.23-44.21%13.67M
3CMPX$1.22-32.97%50.96M
4TGL$2.09-29.39%1.45M
5NFE$8.15-24.72%1.94M
6ORIS$1.83-24.38%65.62M
7VRME$1.05-24.28%3.02M
8XNDU$5.77-21.78%28.67M
9IPW$1.20-21.05%705.23K
10EDRY$53.99-20.57%
11MKDW$1.72-20.37%
12HCWC$11.33-19.93%175.75K
13BWET$683.28-18.07%
14CRMU$2.89-16.23%7.2M
15SUPX$7.52-14.93%6.06M
16EVER$19.57-14.30%4.67M
17PTNM$10.39-14.27%1.51M
18SNDQ$9.17-13.73%54.55M
19GLND$2.50-13.19%286.26M
20VEEE$14.99-13.05%295.73K
21FFAI$1.43-12.58%917.63K
22SST$3.40-12.37%379.75K
23CEPT$11.78-12.22%1.04M
24CLDX$33.49-11.61%25.04M
25GSHD$45.79-11.44%849.74K

Snapshot of liquid US common stock (price ≥ $1, with meaningful volume) ranked by session % move; warrants, units and sub-dollar names are filtered out. Final once the session closes; 15-minute delayed while it's live. For information only — not financial advice.

About regular session movers

The regular session runs from 9:30 a.m. to 4:00 p.m. ET, and it's where the real volume — and the real moves — happen. A stock leading the gainers list on heavy volume is usually riding a fresh catalyst: an earnings beat, upgraded guidance, a contract, a sympathy move within a hot sector, or a technical breakout that's attracting momentum traders. The losers list is the mirror image, and it's just as useful — for spotting breakdowns, failed setups, and oversold bounce candidates.

Percentage move alone doesn't tell the whole story. A 30% move on a few thousand shares is noise; the same move on millions of shares with rising relative volume is a real event. That's why traders pair the gainers and losers list with volume, relative volume and the chart — to separate the durable trends from the one-bar spikes. The names that combine a large move, heavy volume and a clean technical pattern are where the highest-quality day-trade and swing setups come from.

StockSetups scans the entire ~12,300-name US universe in real time during the session and after the close, classifying setups into four ranked lanes with a trade plan on each. This public list shows the final standings once the 4:00 p.m. close is in (15-minute delayed while the session is still live); the live boards and the nightly scan are inside the app.

Frequently asked

What are the top gainers and losers today?

The stocks with the largest positive and negative percentage moves during today's regular session across the whole US market — measured from the prior close to the 4:00 p.m. ET close. This page ranks them with price, percent change and volume: the final standings once the session closes, and a 15-minute-delayed view while it's still live.

What makes a stock a top mover?

Usually a catalyst — earnings, guidance, news, an analyst rating change, a sector move, or a technical breakout — combined with above-average volume. The biggest, most durable moves tend to come on heavy relative volume rather than thin trading.

How can I find the best setups among the movers?

Look for a large move backed by heavy volume and a clean chart pattern near a key level. StockSetups does this automatically — it scans the full market and ranks setups into four lanes with an entry, stop and target on each.

Get daily signals & real-time alerts.

StockSetups scans ~12,300 US stocks & ETFs after every close and sorts every long setup into four ranked lanes — each with a trade plan — plus an always-on engine firing 35+ real-time intraday alerts. Free for 14 days, cancel in one click.

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