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XERS Xeris Biopharma Holdings, Inc. stock chart & analysis

Conviction 4HealthcareScan · Fri, Nov 6, 2026

Xeris Biopharma Holdings, Inc. (XERS) closed at $15.20 (+16.21%) on Nov 6, 2026. Price is above its 50-day and above its 200-day moving average. RSI(14) 82, RS Rating 99, at a 52-week high, +93.5% year to date. Sector: Healthcare · Pharmaceutical Preparations.

XERS$15.20+16.21%
ResistanceSupportVol 14Insider sell
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Xeris Biopharma Holdings, Inc.Pharmaceutical Preparationswww.xerispharma.com ↗
Price15.20
Change+16.21%
Gap+5.43%
Rel volume2.78×
Avg volume3M
Avg $ vol34.94M
SMA 2010.84
SMA 509.62
SMA 2007.61
Price vs 50+57.83%
Price vs 200+99.68%
MA stackbullish
50/200 cross—
Supertrendup · 11.69
RSI (14)82
MACD hist0.31
MACD crossbull · 1d
Stoch %K / %D100 / 74
ADX (14)36
+DI / −DI53 / 11
RSI divergence—
MACD divergence—
ATR %5.19%
ADR %5.13%
52w high15.21
52w low5.25
From 52w high-0.13%
Above 52w low+189.33%
New 52w highYes
SqueezeOff
Bollinger width44.04%
%B1.41
Donchian pos99.64%
Donchian high15.21
Donchian low9.73
AVWAP (52w high)14.65
vs AVWAP high+3.69%
AVWAP (52w low)8.45
vs AVWAP low+79.68%
OBV trendUp
Chaikin MF (20)0.07
Today vs 20d2.78×
Avg vol (14d)3.26M
Avg vol (20d)3M
Avg $ vol (20d)34.94M
Market cap2.78B
RS Rating99 / 99
RS 3m (vs SPY)+94.98%
RS 6m (vs SPY)+132.92%
RS line new highYes
Trend template8/8
Technical rank99.6
1 week+41.83%
1 month+49.07%
3 months+90.11%
6 months+132.62%
1 year+53.90%
YTD+93.50%
P/E5009.41
P/B56.89
P/S9.51
P/FCF100.77
EPS0.0000
Div yield—
ROE1.14%
ROA0.13%
Debt/Eq5.20
Current2.15
EV/EBITDA110.56
Gross margin—
Net margin0.19%
Rev growth43.72%
EPS growth101.01%
Price target16.50
Target upside8.62%
Analyst ratingBuy
Institutional67.18%
Ent. value2.9B
Revenue107.22M
Net income11.29M
Gross profit—
Free cash flow27.54M
IndustryPharmaceutical Preparations
ExchangeNasdaq
Shares out172.64M
Employees435
ListedThu, Jun 21, 2018
Free float153.98M
Float %92.8%
Short interest—
Days to cover—
Short volume18.2%
Squeeze score—
Next earnings—
EPS forecast—
Last EPS vs est$0.06 vs $0.02
Last surprise+200.0% beat
Setup gradeD
Conviction4 / 100
Pattern quality—
Tech rank99.6 / 100
Group rank23 / 100
Status laneNo active setup
Setup direction—
Pattern family
Resistance11.37
Support9.38
Days since event—
Candle confirm—

Financials as of Wed, Sep 30, 2026 · quarterly.

XERS technical analysis

Trend

XERS is in an uptrend: price is above the 50-day, which is above the 200-day moving average. It closed 57.8% above the 50-day ($9.62) and 99.7% above the 200-day ($7.61). ADX(14) at 36 points to a strong, established trend. It meets 8 of 8 trend-template criteria.

Momentum

RSI(14) is 82, in overbought territory. MACD crossed above its signal line one session ago. Its RS Rating of 99 puts its weighted 12-month performance ahead of about 99% of the US market, and its RS line is at a new high.

Volume and volatility

Volume on the latest session ran 2.8× its 20-day average. It trades about $34.9M a day on average. ATR(14) is $0.7887, 5.2% of price — its typical daily range. On-balance volume is trending up. Chaikin Money Flow (0.07) shows accumulation.

Key levels

The chart pattern's support is $9.38 and its resistance $11.37. The 52-week range is $5.25 to $15.21, and price sits at the high. The VWAP anchored at the 52-week high is $14.65, below price.

Performance

XERS returned +41.8% (1 week), +49.1% (1 month), +90.1% (3 months), +132.6% (6 months), +53.9% (1 year), +93.5% (year to date).

About Xeris Biopharma Holdings, Inc.

Xeris Biopharma Holdings Inc is a commercial-stage biopharmaceutical company focused on developing and commercializing therapies for people with chronic endocrine and neurological diseases in the United States. It offers Recorlev for the treatment of endogenous hypercortisolemia in patients with Cushing's syndrome; Gvoke for the treatment of severe hypoglycemia; and Keveyis for the treatment of Primary Periodic Paralysis (PPP). Additionally, the company is advancing its Phase 3-ready pipeline product, XP-8121, a once-weekly subcutaneous injection of levothyroxine, which leverages its proprietary technology, XeriSol.

Pharmaceutical Preparations · Listed 2018 · 435 employees

Insider activity

SEC Form 4 transactions in XERS · open-market 6 sells

InsiderSideShares
McCulloch Kevin
See Remarks · Common Stock · 2026-11-05
Sell25K
McCulloch Kevin
See Remarks · Common Stock · 2026-11-02
Sell15K
Pieper Steven
See Remarks · Common Stock · 2026-11-02
Sell5K
Taddese Menassie
Director · Common Stock · 2026-11-02
Grant22.36K
Taddese Menassie
Director · Stock Option (Right to Buy) · 2026-11-02
Grant31.5K
Hecht Beth
See Remarks · Common Stock · 2026-11-02
Sell25K
McCulloch Kevin
See Remarks · Common Stock · 2026-08-01
Tax21.92K
Shannon John Patrick Jr
See Remarks · Common Stock · 2026-08-01
Tax36.65K
Pieper Steven
See Remarks · Common Stock · 2026-08-12
Sell5K
Pieper Steven
See Remarks · Common Stock · 2026-07-07
Sell27.6K

SEC filings

EDGAR filings in XERS · 10 recent

EDGAR →

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