Skip to content
Stock screener

PRAX Praxis Precision Medicines, Inc. stock chart & analysis

Conviction 41HealthcareScan · Fri, Nov 6, 2026

Praxis Precision Medicines, Inc. (PRAX) closed at $277.62 (+5.72%) on Nov 6, 2026. Price is below its 50-day and below its 200-day moving average. RSI(14) 51, RS Rating 93, -29.3% from its 52-week high, -5.8% year to date. Sector: Healthcare · Pharmaceutical Preparations.

PRAX$277.62+5.72%
ResistanceSupportVol 14Insider sellCongress buyCongress sell
Loading chart…
Praxis Precision Medicines, Inc.Pharmaceutical Preparationswww.praxismedicines.com ↗
Price277.62
Change+5.72%
Gap+0.68%
Rel volume0.68×
Avg volume476.57K
Avg $ vol124.44M
SMA 20264.56
SMA 50291.73
SMA 200313.95
Price vs 50-4.86%
Price vs 200-11.60%
MA stackbearish
50/200 cross—
Supertrendup · 248.81
RSI (14)51
MACD hist3.19
MACD cross—
Stoch %K / %D61 / 59
ADX (14)18
+DI / −DI17 / 21
RSI divergence—
MACD divergence—
ATR %5.17%
ADR %4.84%
52w high392.70
52w low159.74
From 52w high-29.33%
Above 52w low+73.75%
New 52w highNo
SqueezeOff
Bollinger width23.25%
%B0.71
Donchian pos70.06%
Donchian high294.95
Donchian low236.80
AVWAP (52w high)293.27
vs AVWAP high-5.36%
AVWAP (52w low)288.00
vs AVWAP low-3.63%
OBV trendFlat
Chaikin MF (20)-0.09
Today vs 20d0.68×
Avg vol (14d)400.97K
Avg vol (20d)476.57K
Avg $ vol (20d)124.44M
Market cap7.75B
RS Rating93 / 99
RS 3m (vs SPY)-19.50%
RS 6m (vs SPY)-15.60%
RS line new highNo
Trend template2/8
Technical rank42.7
1 week-2.93%
1 month+5.31%
3 months-24.37%
6 months-15.90%
1 year+68.57%
YTD-5.84%
P/E-25.55
P/B5.78
P/S—
P/FCF-31.10
EPS-13.48
Div yield—
ROE-22.61%
ROA-21.82%
Debt/Eq—
Current15.73
EV/EBITDA—
Gross margin—
Net margin—
Rev growth-100.00%
EPS growth-65.88%
Price target726.07
Target upside161.61%
Analyst ratingBuy
Institutional139.17%
Ent. value7.27B
Revenue—
Net income-83.72M
Gross profit—
Free cash flow-249.12M
IndustryPharmaceutical Preparations
ExchangeNasdaq
Shares out27.88M
Employees11K
ListedFri, Oct 16, 2020
Free float27.8M
Float %99.7%
Short interest—
Days to cover—
Short volume62.7%
Squeeze score—
Next earningsNov 9 · pre-mkt (3d)
EPS forecast−$3.68 · 8 est
Last EPS vs est−$2.87 vs −$3.60
Last surprise+20.3% beat
Setup gradeD
Conviction41 / 100
Pattern quality—
Tech rank42.7 / 100
Group rank23 / 100
Status laneNo active setup
Setup direction—
Pattern family
Resistance297.04
Support243.82
Days since event—
Candle confirm—

Financials as of Tue, Jun 30, 2026 · quarterly.

PRAX technical analysis

Trend

PRAX is in a downtrend: price is below the 50-day, which is below the 200-day moving average. It closed 4.9% below the 50-day ($291.73) and 11.6% below the 200-day ($313.95). ADX(14) at 18 points to a weak trend — more range than direction. It meets 2 of 8 trend-template criteria.

Momentum

RSI(14) is 51, in the bullish half of its range. The MACD histogram is positive. Its RS Rating of 93 puts its weighted 12-month performance ahead of about 93% of the US market.

Volume and volatility

Volume on the latest session ran 0.7× its 20-day average. It trades about $124.4M a day on average. ATR(14) is $14.35, 5.2% of price — its typical daily range. Chaikin Money Flow (-0.09) shows distribution.

Key levels

The chart pattern's support is $243.82 and its resistance $297.04. The 52-week range is $159.74 to $392.70; price is 29.3% below the high and 73.8% above the low. The VWAP anchored at the 52-week high is $293.27, above price.

Performance

PRAX returned -2.9% (1 week), +5.3% (1 month), -24.4% (3 months), -15.9% (6 months), +68.6% (1 year), -5.8% (year to date).

About Praxis Precision Medicines, Inc.

Praxis Precision Medicines Inc is a clinical-stage biopharmaceutical company. It is engaged in translating genetic insights into the development of therapies for patients affected by central nervous system disorders characterized by a neuronal excitation-inhibition imbalance. The company applies genetic insights to the discovery and development of therapies for neurological disorders through two proprietary platforms: Cerebrum and Solidus. It has established a diversified, multimodal CNS portfolio with four clinical-stage product candidates across movement disorders and epilepsy, which include Ulixacaltamide, Relutrigine, Vormatrigine, and Elsunersen. The firm operates in only one segment and is focused on discovering and developing therapies for CNS disorders.

Pharmaceutical Preparations · Listed 2020 · 10,998 employees

Congress activity

Disclosed STOCK Act trades in PRAX · 2 recent

All disclosures →
MemberSideAmount
Gilbert Cisneros
Gilbert Cisneros
house · D · CA · traded 2026-09-29
Buy$1K–$15K
Gilbert Cisneros
Gilbert Cisneros
house · D · CA · traded 2026-07-30
Buy$1K–$15K

Insider activity

SEC Form 4 transactions in PRAX · open-market 6 sells

InsiderSideShares
Souza Marcio
Chief Executive Officer · Common Stock · 2026-07-08
Gift20.52K
Souza Marcio
Chief Executive Officer · Common Stock · 2026-07-08
Gift2.6K
DeSimone Jill
Director · Common Stock · 2026-06-24
Sell1.24K
DeSimone Jill
Director · Common Stock · 2026-06-24
Sell999
DeSimone Jill
Director · Common Stock · 2026-06-24
Sell1.75K
DeSimone Jill
Director · Common Stock · 2026-06-24
Sell1.28K
DeSimone Jill
Director · Common Stock · 2026-06-24
Exercise8.57K
DeSimone Jill
Director · Common Stock · 2026-06-24
Exercise3.03K
DeSimone Jill
Director · Common Stock · 2026-06-24
Sell10
DeSimone Jill
Director · Common Stock · 2026-06-24
Sell120

SEC filings

EDGAR filings in PRAX · 10 recent

EDGAR →

Get daily signals & real-time alerts.

StockSetups scans ~12,300 US stocks & ETFs after every close and sorts every long setup into four ranked lanes — each with a trade plan — plus an always-on engine firing 35+ real-time intraday alerts. Free for 7 days, no credit card.

Start free — 7-day trial, no card →

Educational data, not financial advice. Patterns, levels and the trade plan are algorithmic, not a recommendation to trade.