Skip to content
Stock screener

LYEL Lyell Immunopharma, Inc. stock chart & analysis

Conviction 9HealthcareScan · Fri, Nov 6, 2026

Lyell Immunopharma, Inc. (LYEL) closed at $14.86 (-0.93%) on Nov 6, 2026. Price is above its 50-day and below its 200-day moving average. RSI(14) 74, RS Rating 60, -67.0% from its 52-week high, -51.8% year to date. Sector: Healthcare · Pharmaceutical Preparations.

LYEL$14.86-0.93%
ResistanceSupportVol 14Insider buyInsider sell
Loading chart…
Lyell Immunopharma, Inc.Pharmaceutical Preparationswww.lyell.com ↗
Price14.86
Change-0.93%
Gap+5.60%
Rel volume2.12×
Avg volume247.65K
Avg $ vol2.94M
SMA 2010.32
SMA 5010.86
SMA 20016.60
Price vs 50+36.62%
Price vs 200-10.63%
MA stackmixed
50/200 cross—
Supertrendup · 11.14
RSI (14)74
MACD hist0.72
MACD cross—
Stoch %K / %D77 / 81
ADX (14)38
+DI / −DI39 / 8
RSI divergence—
MACD divergence—
ATR %8.32%
ADR %9.94%
52w high45.00
52w low7.20
From 52w high-67.03%
Above 52w low+106.18%
New 52w highNo
SqueezeOff
Bollinger width88.40%
%B1.00
Donchian pos80.13%
Donchian high16.73
Donchian low7.20
AVWAP (52w high)16.64
vs AVWAP high-10.83%
AVWAP (52w low)11.95
vs AVWAP low+24.12%
OBV trendFlat
Chaikin MF (20)0.10
Today vs 20d2.12×
Avg vol (14d)252.17K
Avg vol (20d)247.65K
Avg $ vol (20d)2.94M
Market cap364.73M
RS Rating60 / 99
RS 3m (vs SPY)+8.39%
RS 6m (vs SPY)-22.95%
RS line new highNo
Trend template3/8
Technical rank56.2
1 week+34.38%
1 month+68.77%
3 months+3.52%
6 months-23.25%
1 year-10.31%
YTD-51.80%
P/E-1.33
P/B1.89
P/S—
P/FCF-2.42
EPS-16.06
Div yield—
ROE-142.41%
ROA-100.22%
Debt/Eq—
Current4.02
EV/EBITDA-1.06
Gross margin—
Net margin—
Rev growth-40.98%
EPS growth19.98%
Price target—
Target upside—
Analyst rating—
Institutional49.17%
Ent. value272.67M
Revenue3K
Net income-45.53M
Gross profit—
Free cash flow-150.8M
IndustryPharmaceutical Preparations
ExchangeNasdaq
Shares out23.33M
Employees161
ListedThu, Jun 17, 2021
Free float6.6M
Float %31.1%
Short interest—
Days to cover—
Short volume56.2%
Squeeze score—
Next earnings—
EPS forecast—
Last EPS vs est—
Last surprise—
Setup gradeD
Conviction9 / 100
Pattern quality—
Tech rank56.2 / 100
Group rank23 / 100
Status laneNo active setup
Setup direction—
Pattern family
Resistance14.18
Support7.70
Days since event—
Candle confirm—

Financials as of Wed, Sep 30, 2026 · quarterly.

LYEL technical analysis

Trend

LYEL's moving averages are mixed — no clean uptrend or downtrend. It closed 36.6% above the 50-day ($10.86) and 10.6% below the 200-day ($16.60). ADX(14) at 38 points to a strong, established trend. It meets 3 of 8 trend-template criteria.

Momentum

RSI(14) is 74, in overbought territory. The MACD histogram is positive. Its RS Rating of 60 puts its weighted 12-month performance ahead of about 60% of the US market.

Volume and volatility

Volume on the latest session ran 2.1× its 20-day average. It trades about $2.9M a day on average. ATR(14) is $1.23, 8.3% of price — its typical daily range. Chaikin Money Flow (0.10) shows accumulation.

Key levels

The chart pattern's support is $7.70 and its resistance $14.18. The 52-week range is $7.20 to $45.00; price is 67.0% below the high and 106.2% above the low. The VWAP anchored at the 52-week high is $16.64, above price.

Performance

LYEL returned +34.4% (1 week), +68.8% (1 month), +3.5% (3 months), -23.3% (6 months), -10.3% (1 year), -51.8% (year to date).

About Lyell Immunopharma, Inc.

Lyell Immunopharma Inc s a late-stage clinical cell therapy company advancing a pipeline of proprietary next-generation autologous chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The Company's product candidate, rondecabtagene autoleucel (ronde-cel, also known as LYL314), is an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development for large B-cell lymphoma (LBCL). The Company has recently acquired exclusive rights outside of mainland China, Hong Kong, Macau and Taiwan, to a novel guanylyl cyclase C (GCC)-targeted CAR T-cell product candidate in early clinical development for refractory metastatic colorectal cancer (mCRC) and other GCC-expressing cancers.

Pharmaceutical Preparations · Listed 2021 · 161 employees

Insider activity

SEC Form 4 transactions in LYEL · open-market 2 buys · 7 sells

InsiderSideShares
ARCH Venture Partners IX, LLC
10% owner · Common Stock · 2026-11-04
Buy2.32M
ARCH Venture Fund XIII, L.P.
10% owner · Common Stock · 2026-11-04
Buy2.32M
Hill Stephen J.
Chief Operating Officer · Common Stock · 2026-08-21
Sell989
Lee Gary K.
Chief Scientific Officer · Common Stock · 2026-08-21
Sell1.46K
Seely Lynn
President and CEO · Common Stock · 2026-08-21
Sell9.59K
Bulis Veronica Sanchez
VP, Corporate Controller · Common Stock · 2026-08-10
Sell621
Hill Stephen J.
Chief Operating Officer · Common Stock · 2026-08-10
Sell89
Lee Gary K.
Chief Scientific Officer · Common Stock · 2026-08-10
Sell131
Seely Lynn
President and CEO · Common Stock · 2026-08-10
Sell390
Innovative Cellular Therapeutics Holdings Ltd
10% owner · Common Stock · 2026-07-27
Dispose38.5K

SEC filings

EDGAR filings in LYEL · 10 recent

EDGAR →

Get daily signals & real-time alerts.

StockSetups scans ~12,300 US stocks & ETFs after every close and sorts every long setup into four ranked lanes — each with a trade plan — plus an always-on engine firing 35+ real-time intraday alerts. Free for 7 days, no credit card.

Start free — 7-day trial, no card →

Educational data, not financial advice. Patterns, levels and the trade plan are algorithmic, not a recommendation to trade.