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IOVA Iovance Biotherapeutics, Inc. stock chart & analysis

Conviction 45HealthcareScan · Fri, Nov 6, 2026

Iovance Biotherapeutics, Inc. (IOVA) closed at $8.04 (+3.88%) on Nov 6, 2026. Price is below its 50-day and above its 200-day moving average. RSI(14) 33, RS Rating 99, -47.7% from its 52-week high, +194.5% year to date. Sector: Healthcare · Biological Products, (No Diagnostic Substances).

IOVA$8.04+3.88%
ResistanceSupportVol 14
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Why IOVA moved

From the StockSetups movers recaps that covered IOVA, newest first. A recap states what was known that day.

Iovance Biotherapeutics, Inc.Biological Products, (No Diagnostic Substances)www.iovance.com ↗
Price8.04
Change+3.88%
Gap+4.78%
Rel volume0.89×
Avg volume15.5M
Avg $ vol171.41M
SMA 2012.30
SMA 5011.38
SMA 2005.98
Price vs 50-29.32%
Price vs 200+34.40%
MA stackmixed
50/200 cross—
Supertrenddown · 11.38
RSI (14)33
MACD hist-0.79
MACD cross—
Stoch %K / %D5 / 7
ADX (14)42
+DI / −DI15 / 41
RSI divergence—
MACD divergence—
ATR %13.66%
ADR %7.99%
52w high15.37
52w low2.08
From 52w high-47.69%
Above 52w low+286.54%
New 52w highNo
SqueezeOff
Bollinger width92.36%
%B0.12
Donchian pos5.24%
Donchian high15.37
Donchian low7.64
AVWAP (52w high)10.22
vs AVWAP high-21.30%
AVWAP (52w low)5.53
vs AVWAP low+45.37%
OBV trendDown
Chaikin MF (20)-0.23
Today vs 20d0.89×
Avg vol (14d)17.58M
Avg vol (20d)15.5M
Avg $ vol (20d)171.41M
Market cap3.72B
RS Rating99 / 99
RS 3m (vs SPY)+30.49%
RS 6m (vs SPY)+122.40%
RS line new highNo
Trend template6/8
Technical rank63.0
1 week-5.19%
1 month-39.59%
3 months+25.62%
6 months+122.10%
1 year+344.20%
YTD+194.51%
P/E-9.51
P/B4.58
P/S14.12
P/FCF-11.06
EPS-1.09
Div yield—
ROE-48.11%
ROA-39.44%
Debt/Eq—
Current5.20
EV/EBITDA-9.38
Gross margin34.28%
Net margin-148.38%
Rev growth60.60%
EPS growth-5.05%
Price target14.80
Target upside84.08%
Analyst ratingBuy
Institutional70.37%
Ent. value3.66B
Revenue121.47M
Net income-22.27M
Gross profit73.44M
Free cash flow-336.24M
IndustryBiological Products, (No Diagnostic Substances)
ExchangeNasdaq
Shares out446.5M
Employees975
ListedWed, May 26, 2010
Free float372.08M
Float %90.3%
Short interest—
Days to cover—
Short volume43.6%
Squeeze score—
Next earnings—
EPS forecast—
Last EPS vs est−$0.05 vs −$0.09
Last surprise+44.4% beat
Setup gradeD
Conviction45 / 100
Pattern quality—
Tech rank63.0 / 100
Group rank23 / 100
Status laneNo active setup
Setup direction—
Pattern family
Resistance15.34
Support9.99
Days since event—
Candle confirm—

Financials as of Wed, Sep 30, 2026 · quarterly.

IOVA technical analysis

Trend

IOVA's moving averages are mixed — no clean uptrend or downtrend. It closed 29.3% below the 50-day ($11.38) and 34.4% above the 200-day ($5.98). ADX(14) at 42 points to a strong, established trend. It meets 6 of 8 trend-template criteria.

Momentum

RSI(14) is 33, in the bearish half of its range. The MACD histogram is negative. Its RS Rating of 99 puts its weighted 12-month performance ahead of about 99% of the US market.

Volume and volatility

Volume on the latest session ran 0.9× its 20-day average. It trades about $171.4M a day on average. ATR(14) is $1.10, 13.7% of price — its typical daily range. On-balance volume is trending down. Chaikin Money Flow (-0.23) shows distribution.

Key levels

The chart pattern's support is $9.99 and its resistance $15.34. The 52-week range is $2.08 to $15.37; price is 47.7% below the high and 286.5% above the low. The VWAP anchored at the 52-week high is $10.22, above price.

Performance

IOVA returned -5.2% (1 week), -39.6% (1 month), +25.6% (3 months), +122.1% (6 months), +344.2% (1 year), +194.5% (year to date).

About Iovance Biotherapeutics, Inc.

Iovance Biotherapeutics Inc is a clinical-stage biopharmaceutical company, pioneering a transformational approach to treating cancer by harnessing the human immune system's ability to recognize and destroy diverse cancer cells using therapies personalized for each patient. The company is preparing for potential U.S. regulatory approvals and commercialization of the first autologous T-cell therapy to address a solid tumor cancer. It operates in one segment, focusing on innovating, developing, and commercializing therapies using its autologous TIL cell therapies for patients with solid tumor cancers. Geographically, the company operates in United States and Rest of the World.

Biological Products, (No Diagnostic Substances) · Listed 2010 · 975 employees

Insider activity

SEC Form 4 transactions in IOVA

InsiderSideShares
Kirby Daniel Gordon
Chief Commercial Officer · Common Stock · 2026-08-10
Exercise10K
Kirby Daniel Gordon
Chief Commercial Officer · Common Stock · 2026-08-10
Tax2.44K
Kirby Daniel Gordon
Chief Commercial Officer · Restricted Stock Units · 2026-08-10
Exercise10K
Roche Corleen M.
Chief Financial Officer · Common Stock · 2026-08-06
Exercise49.99K
Roche Corleen M.
Chief Financial Officer · Common Stock · 2026-08-06
Tax21.24K
Roche Corleen M.
Chief Financial Officer · Restricted Stock Units · 2026-08-06
Exercise49.99K
Countouriotis Athena
Director · Deferred Restricted Stock Unit · 2026-06-16
Grant90.32K
Dukes Iain D.
Director · Deferred Restricted Stock Unit · 2026-06-16
Grant180.63K
Puri Raj K.
Chief Regulatory Officer · Restricted Stock Units · 2026-06-16
Grant15K
Maynard Ryan D
Director · Deferred Restricted Stock Unit · 2026-06-16
Grant90.32K

SEC filings

EDGAR filings in IOVA · 10 recent

EDGAR →

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