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AGIO Agios Pharmaceuticals, Inc. stock chart & analysis

Conviction 45HealthcareScan · Fri, Nov 6, 2026

Agios Pharmaceuticals, Inc. (AGIO) closed at $29.41 (+4.03%) on Nov 6, 2026. Price is below its 50-day and below its 200-day moving average. RSI(14) 38, RS Rating 22, -36.1% from its 52-week high, +7.9% year to date. Sector: Healthcare · Pharmaceutical Preparations.

AGIO$29.41+4.03%
ResistanceSupportVol 14Insider sellCongress buyCongress sell
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Agios Pharmaceuticals, Inc.Pharmaceutical Preparationswww.agios.com ↗
Price29.41
Change+4.03%
Gap+0.88%
Rel volume1.58×
Avg volume1.37M
Avg $ vol44.74M
SMA 2033.48
SMA 5033.27
SMA 20031.76
Price vs 50-11.69%
Price vs 200-7.49%
MA stackmixed
50/200 cross—
Supertrenddown · 35.49
RSI (14)38
MACD hist-0.80
MACD crossbear · 4d
Stoch %K / %D16 / 13
ADX (14)25
+DI / −DI16 / 34
RSI divergence—
MACD divergence—
ATR %6.74%
ADR %5.39%
52w high46.00
52w low22.24
From 52w high-36.13%
Above 52w low+32.10%
New 52w highNo
SqueezeOff
Bollinger width40.01%
%B0.19
Donchian pos16.31%
Donchian high38.69
Donchian low27.57
AVWAP (52w high)30.26
vs AVWAP high-2.91%
AVWAP (52w low)30.23
vs AVWAP low-2.82%
OBV trendFlat
Chaikin MF (20)-0.01
Today vs 20d1.58×
Avg vol (14d)1.4M
Avg vol (20d)1.37M
Avg $ vol (20d)44.74M
Market cap1.76B
RS Rating22 / 99
RS 3m (vs SPY)-4.98%
RS 6m (vs SPY)+6.02%
RS line new highNo
Trend template4/8
Technical rank46.5
1 week-3.83%
1 month-7.96%
3 months-9.85%
6 months+5.72%
1 year-27.47%
YTD+7.94%
P/E-4.26
P/B1.79
P/S32.52
P/FCF-4.66
EPS-7.12
Div yield—
ROE-42.15%
ROA-38.79%
Debt/Eq—
Current9.69
EV/EBITDA—
Gross margin88.26%
Net margin-764.01%
Rev growth48.03%
EPS growth-161.27%
Price target45.80
Target upside55.89%
Analyst ratingBuy
Institutional123.45%
Ent. value1.63B
Revenue55.38M
Net income-65.05M
Gross profit52.86M
Free cash flow-377.29M
IndustryPharmaceutical Preparations
ExchangeNasdaq
Shares out—
Employees540
ListedWed, Jul 24, 2013
Free float57.6M
Float %98.3%
Short interest—
Days to cover—
Short volume61.3%
Squeeze score—
Next earnings—
EPS forecast—
Last EPS vs est−$1.09 vs −$1.32
Last surprise+17.4% beat
Setup gradeD
Conviction45 / 100
Pattern quality—
Tech rank46.5 / 100
Group rank23 / 100
Status laneNo active setup
Setup direction—
Pattern family
Resistance37.03
Support29.74
Days since event—
Candle confirm—

Financials as of Wed, Sep 30, 2026 · quarterly.

AGIO technical analysis

Trend

AGIO's moving averages are mixed — no clean uptrend or downtrend. It closed 11.7% below the 50-day ($33.27) and 7.5% below the 200-day ($31.76). ADX(14) at 25 points to a moderate trend. It meets 4 of 8 trend-template criteria.

Momentum

RSI(14) is 38, in the bearish half of its range. MACD crossed below its signal line 4 sessions ago. Its RS Rating of 22 puts its weighted 12-month performance ahead of about 22% of the US market.

Volume and volatility

Volume on the latest session ran 1.6× its 20-day average. It trades about $44.7M a day on average. ATR(14) is $1.98, 6.7% of price — its typical daily range.

Key levels

The chart pattern's support is $29.74 and its resistance $37.03. The 52-week range is $22.24 to $46.00; price is 36.1% below the high and 32.1% above the low. The VWAP anchored at the 52-week high is $30.26, above price.

Performance

AGIO returned -3.8% (1 week), -8.0% (1 month), -9.8% (3 months), +5.7% (6 months), -27.5% (1 year), +7.9% (year to date).

About Agios Pharmaceuticals, Inc.

Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.

Pharmaceutical Preparations · Listed 2013 · 540 employees

Congress activity

Disclosed STOCK Act trades in AGIO · 4 recent

All disclosures →
MemberSideAmount
Gilbert Cisneros
Gilbert Cisneros
house · D · CA · traded 2026-08-20
Buy$1K–$15K
Gilbert Cisneros
Gilbert Cisneros
house · CA · traded 2026-03-03
Buy$1K–$15K
Gilbert Cisneros
Gilbert Cisneros
house · D · CA · traded 2025-04-17
Buy$1K–$15K
Gilbert Cisneros
Gilbert Cisneros
house · D · CA · traded 2025-01-29
Buy$1K–$15K

Insider activity

SEC Form 4 transactions in AGIO · open-market 2 sells

InsiderSideShares
Gheuens Sarah
Chief Medical Officer · Common stock · 2026-10-26
Exercise7.87K
Gheuens Sarah
Chief Medical Officer · Common stock · 2026-10-26
Sell7.87K
Gheuens Sarah
Chief Medical Officer · Stock options (right to buy) · 2026-10-26
Exercise7.87K
Gheuens Sarah
Chief Medical Officer · Common stock · 2026-08-04
Sell30K
Backstrom Jay T.
Director · Common stock · 2026-07-08
Grant1.45K
Backstrom Jay T.
Director · Restricted stock units · 2026-07-08
Exercise1.45K
CAPELLO JEFFREY D
Director · Common stock · 2026-06-13
Exercise1.98K
CAPELLO JEFFREY D
Director · Restricted stock units · 2026-06-13
Exercise1.98K
Owen Adams Catherine
Director · Common stock · 2026-06-13
Exercise1.98K
Owen Adams Catherine
Director · Restricted stock units · 2026-06-13
Exercise1.98K

SEC filings

EDGAR filings in AGIO · 10 recent

EDGAR →

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